Niacinamide B-3 (100 caps)

Niacinamide is one of the two principal forms of the B-complex vitamin niacin. It is a water-soluble vitamin that plays a crucial role in various biological processes and has unique nutritional and pharmacological properties.

• Supports energy production
• Facilitates the synthesis of fatty acids, cholesterol, and steroids
• Involved in signal transduction
• Maintains the integrity of the genome
• May help prevent type 1 diabetes mellitus
• Has antioxidant and anti-inflammatory properties
• May aid in some cancer therapies
• Supports general well-being and anti-aging
• Traditionally used to treat pellagra

The typical supplemental dosage ranges from 20 to 100 milligrams daily. The correct dosage for Niacinamide B3 is indicated on the label. It is recommended to consult with a healthcare provider for personalized dosage guidance, especially for individuals with circulatory or cardiovascular issues.

Niacinamide has been found to enhance the activity of Sir2p, a protein involved in cellular life extension and gene silencing. Increasing intracellular NAD levels through niacinamide supplementation may mimic the benefits of calorie-restricted diets and help maintain a balance of silent and active genes.

Niacinamide, along with other supplements like glucosamine, SAMe, selenium, and fish oil, has been shown to provide superior alternatives to nonsteroidal anti-inflammatory drugs (NSAIDs) for the treatment of arthritis. These supplements modulate signal transduction pathways and cytokine activity, which contribute to arthritis symptoms.